BIOGRUND offers knowledge and experience from 20 years of formulation work in the areas of film coating, sugar-coating, tabletting, colouring and excipients. Thereby, we refer to the cooperation with our customers from the pharmaceutical, food and cosmetics industry. Developments always take place with the customer and are tailor-made. Thus, the know-how complements each other and both parties benefit and learn from it. The knowledge gained in this way flows daily into our development work. The close contact and cooperation with universities extends our know-how as well as that of the students. Passing on our experience to emerging scientists and generating knowledge through them helps us to stay innovative. An active exchange on new topics, experiences and interesting facts, as well as the search for common solutions to problems through a large network is ensured by our membership in industry associations, such as e.g. the IPEC.
VIDEO: Benefits of ready-to-use film coating systems – short & simple explained
BIOGRUND is a specialist for ready-to-use systems. But what exactly is that? Our ready-to-use products are homogeneous dry powder blends that contain all the ingredients for a perfect film coating. They are easily soluble in water or organic solvents. In just one step, the user can prepare a spray suspension ready for use. Ready-to-use powder mixtures for film coating contain film-forming polymers, fillers, pigments, plasticizers and binders. The respective formulation is customized.
The advantages of ready-to-use systems
Preparing a ready-to-use film coating suspension (AquaPolish®)
The benefits of tablet/film coating
Protective film without function. In non-functional films, the tablet core is provided with a thin film coating, to e.g. isolate the drug and thus prevent its volatilization. The protective film improves the mechanical stability, the aesthetics, the identity, the storage conditions and the flow properties as well as the surface structure of the tablet.
Functional protective film. The tablet core is coated with a functional coating, e.g. to achieve an odour or taste masking. Furthermore, it is possible to achieve protection against environmental influences such as oxidation, UV radiation and moisture. Other functions include the targeted or delayed release of the active ingredient, protection against stomach acid, protection of the mucous membrane and reduction of side effects.
The challenge of the film coating process
Before, during and after the film coating process, an operator has to pay attention to a lot of things. Some critical parameters must be set in advance and adjusted during the process. As our graph shows, the following factors play a key role in making the process successful: