Are you in the development phase? Or do you only need a small amount of raw materials / excipients for some of your products? We are just as specialized in these requirements as we are in larger quantities.
High-quality raw materials for your product:
Cellulose Ethers (HPMC)
- In the field of hypromellose polymers (HPMC), our BonuCel® H offers a wide range of standard viscosities (low-/high-viscous)for different application requirements.
- Cellulose ether polymers offer excellent film forming properties and delayed release profiles.
- The high viscosity BonuCel® H grades are designed for a hydrophilic matrix agent.
- BonuCel® H is manufactured to IPEC GMP guidelines and meets all the requirements of USP/NF, Ph.Eur. and JP. The registration number is CAS 9004-65-3.
- The material is provided by BIOGRUND GmbH (Germany) and BIOGRUND US, Inc. (USA).
Hot Melt Coating, Polishing & Waxing
Ready-to-use application for hot melt coating of particles; polishing of sugar-coated tablets; anti-sticking of soft gel capsules.
- water and solvent free application
- no drying times
- provides good moisture sealing, taste masking
- stability for granules and particles
If a shiny surface is requested for sugar-coated tablets, BonuWax® as a mixture of bee wax and carnauba wax can be used to achieve an excellent glossy finishing. Under the principle of friction, a brilliant gloss/shine will be realized, which leads to an aesthetic valorization for sugar-coated tablets.
BonuWax® is formulated with different natural waxes and is highly stable to provide excellent transparency, anti-sticking properties (effective separation) and enhanced mechanical stability/flowability during processing and packaging. Waxed capsules also have higher resistance to external influences like humidity and are easier to swallow.
Hot Melt Extrusion Cleaner
A purge compound for hot melt extrusion terminates difficulties to clean the extruder after processing.
HME Cleaner Plus (GMP) is an almost water-soluble purge compound with a micro-cleansing effect which solves this cleaning difficulty for the HME process. HME Cleaner Plus (GMP) provides effective clean-up because of its high detergency and low residual properties.
galenIQ TM - Isomalt
- Highly functional filler and binder
- Applicability to a wide range of solid and liquid dosage forms
- Suitable for direct compression
- Manufactured under cGMP conditions according to IPEC-PQG requirements for pharmaceutical excipients
- Complies with the current Ph. Eur., BP, USP-NF and JP monographs for Isomalt
- Taste masking properties
- Manufacturer: BENEO GmbH, Germany
BIOGRUND is one of the official distributors.
Tylopur Xtend Nutra® - for extended release profiles
For sustained/extended release of active ingredient. It is suitable for use in tablet formulations for direct tableting. Tylopur Xtend Nutra® is a plant derived cellulose-based ingredient. It has been specially developed for nutraceutical applications and dietary supplements. Viscosity grades: 4000 and 15000 mPas.
Benefits:
– Your active ingredient gains a extended/delayed release profile – naturally.
– Your capsule formulation is optimized into a tablet.
– Get the optimum dosage and smallest possible tablet size.
– Your costs can be reduced: The production of tablets is more cost-effective compared to capsules.
TYLOPUR XTEND NUTRA® is a plant derived product that complies to European and US-American guidelines and guarantees the exclusion of non-conformig ingredients (dioxides, stearates). Manufacturer: ShinEtsu (SE Tylose Gmbh & Co. KG / SE Tylose USA, Inc.)
BIOGRUND is one of the official distributors.
Tylopur ClearCoat Nutra®
Your tablets get an easy-to-make coating with just two natural ingredients: Plant-derived Tylopur ClearCoat Nutra® and water … a naturally clear choice.
- plant-derived cellulose-based excipient
- specially developed for nutraceutical/nutritional applications and dietary supplements
- provides a natural, easy-to-use tablet coating
- is also suitable for use in tablet formulations by granulation
- Manufacturer: ShinEtsu (SE Tylose Gmbh & Co. KG / SE Tylose USA, Inc.)
BIOGRUND is one of the official distributors.
Tylopur® DG - 4T - Polymer for hand sanitizer gel
Hand sanitizer gel is a hydroalcoholic gel formulated with a high level of alcohol. The Center for disease control and prevention (CDC) recommends a minimum of 60 percent alcohol for an alcohol-based hand sanitizer.
Hypromellose (HPMC) has a good solubility in alcohol. The formulation of hand sanitizer gels use polymers as thickener agents to increase the viscosity of the gel. Shin-Etsu HPMC TYLOPUR® DG-4T (Hypromellose 2910) is a suitable thickener for this application due to the stability in and compatibility with organic solvents.
Beside the thickener agent (e.g. HPMC), a humectant (e.g. glycerine, propylene glycol) is needed in the formulation. Additionally, a chelating agent can be used, such as tetra sodium EDTA or sodium citrate. Fragrances and extracts can also be added to the gel. A neutralizing agent, such as sodium hydroxide, can be used to achieve the desired pH.