Efficient, fast & reliable products? Why not!

Easy-to-use ready mixes for tableting. Tailor-made & easy to use.

Direct compression – easy & fast. For years it has been apparent that direct compression of oral dosage forms is becoming increasingly popular. New technologies and excipients make it possible to simplify this production stage. Some wet granulation products can now easily be converted to direct tableting.

Weighing, mixing, lubricating, pressing – sounds simple, it usually is. The success of a perfect direct compressed tablet depends on the amounts of active ingredients and excipients in the tablet mixture, their different particle sizes, flow and compression properties and sensitivities to moisture. Ultimately, the tablet hardness must be firm enough to have low brittleness in order to avoid chipping at the tablet bar and dust formation during further processing. Nevertheless, tablets with a break notch should be easily divisible, as well as not alter the release profile of the active ingredient.

Our excipient blends for direct tableting are tailored to these properties. They specifically affect the property that is to be improved, adjusted or eliminated. Our innovative tableting excipients help replace other undesirable excipients.

Ready-to-use – simply add 0.5 – 10 % of our premix products to the tablet mass and mix.

Challenge us! We assist you with our know-how for your tableting project: Consulting | Development | Color adjustment Tablet analysis | Formulation change | Production | Documentation

Tableting BIOGRUND

Dry binders

CompactCel®
dry binder for high-dose active ingredient tablets
  • Enables the compression of normally non-compressible active ingredients in just one step.
  • Optimizes the flowability of the tablet mass.
  • Increases the tablet hardness.
  • Reduces the friability of the tablet.
  • Delivers a granulated, homogeneous, dry milling of HPC/CMC, PVP/CMC or low viscosity HPC/HPMC.
  • Wet granulation is usually no longer necessary due to the use of CompactCel®.
  • Quality: Pharma | Food

CompactCel® SIL
optimized flow properties & stability
  • Improves flowability of the tablet mass.
  • Better adsorption capacity (of liquids/moisture) & more stability.
  • Higher compression of the tablet mixture and active ingredient.
  • Dry binder granulate of silicon dioxide and HPC/NaCMC or PVP/NaCMC.
  • Wet granulation is usually no longer necessary due to the use of CompactCel® SIL.
  • Quality: Pharma | Food

CompactCel® TC
taste-masking dry binder
  • Neutralizes bad-tasting active ingredients in the tablet mixture. Important for uncoated tablets.
  • Formulation consists of several taste masking raw materials.
  • Premix is also available with all-natural ingredients, for clean label purposes.
  • Quality: Pharma | Food

CompactCel® Natural
Natural dry binder
    • Ingredient premix for direct compression. Based on high quality, natural ingredients.
    • The binder supports clean label strategies for dietetic foods and dietary supplements (e.g. to replace HPC or PVP in the formulation).
    • Quality: Food

CompactCel® Organic
Organic dry binder
    • The natural dry binder for direct tableting.
    • Based on selected natural, certified organic ingredients.
    • The binder supports clean label strategies for dietary foods and supplements.
    • Certified with the EU and US organic food label.
    • Quality: Food

Flow aids | Lubricants | Absorber (oil/moisture)

CompactCel® FLO
natural flow agent
  • Separating agent that loosens up the tablet mass.
  • Improves the flowability of powder mixtures.
  • Provides a clean funnel flow of the powder mass to be processed during both tableting process and capsule filling.
  • Natural premix of various rice additives and phosphate.
  • Free of silicon dioxide.
  • Quality: Pharma | Food

CompactCel® LUB
Lubricant
  • Micronized & homogeneous powder blend.
  • Use of natural lubricants.
  • Free of of magnesium stearate.
  • The lubrication has no influence on the tablet requirements.
  • Reduces wear on punches and prevents sticking to punch faces.
  • Decreases friction at the interface between tablet and die wall.
  • Suitable for the filling & closing of hard gelatine caspules.
  • Quality: Pharma | Food

CompactCel® MAB
Moisture/Oil absorbent
  • Loosening up the tablet mass.
  • Excellent moisture- & oil absorbing properties.
  • Prevents clumping of hydrophilic active ingredients before and during the tableting process.
  • The high absorbent properties are used to make oily substances (e.g. CBD oil / hemp) suitable for the tableting or capsule filling process (Oil to powder).
  • Homogeneous dry milling of moisture-absorbing excipients such as silicon dioxide, calcium carbonate, MCC and/or talc.
  • Formulations with solely natural ingredients are available.
  • Quality: Pharma | Food

Disintegrants

CompactCel® DIS
natural disintegrant

The USDA-organic certified disintegrant enables rapid release of active ingredient from solid oral dosage forms when they come into contact with moisture. EU organic label certification will be available soon. To ensure that its tablet formulation meets clean label requirements, CompactCel® DIS is manufactured using only ingredients from natural sources. It offers a good alternative for synthetic disintegrants, such as cross-linked polymers, crosscarmellose sodium or sodium starch glycolate. The natural tablet mixture helps in rapid release of active ingredient in the stomach after ingestion. It can also be used for the formulation of oral disintegrating tablets (ODT) or chewable tablets.

CompactCel® DIS for direct compression possess several useful properties:
– good hydration
– low gel formation
– good compressibility and flow properties
– faster therapeutic effect (bioavailability)

Sustained release

CompactCel® SR
sustained drug release
  • Retardation. For a sustained release profile of the drug.
  • Forms a reliable gel film through which the active ingredient permanently diffuses.
  • Depending on the active ingredient (easily or poorly soluble), the gelation and thus the release profile can be adjusted.
  • Application is suitable for dry and wet granulation.
  • Micronized and homogeneous dry powder compound of HPMC & NaCMC.
  • Recommended dosage for tablet formulations: 10 – 30 %.
  • Quality: Pharma | Food

Tablet formulation

BonuTab®
customized tablet formulation
  • Tailor-made premix, which already contains e.g. fillers, binders, lubricants, pigments and dyes.
  • One-Step. Only adding the active ingredient before production.
  • Use of only one excipient premix instead of several individual components.
  • Accelerates the tablet manufacturing process.
  • Reduces weighing errors & lumps.
  • Reduces production & analysis costs.
  • Provides consistency from batch to batch | consistent quality.
  • Homogeneous dry powder mixture.
  • Quality: Pharma | Food
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