Hand Sanitizer

Polymer for the preparation

of hand sanitizer gel

Tylopur® DG-4T


Brand-, Product-Owner and Producer.

Polymer for the preparation of hand sanitizer gel

A special Hypromellose type

Hand sanitizer gel is a hydroalcoholic gel formulated with a high level of alcohol. The Center for disease control and prevention (CDC) recommends a minimum of 60 percent alcohol for an alcohol-based hand sanitizer. [1]

Hypromellose (HPMC) has a good solubility in alcohol. The formulation of hand sanitizer gels use polymers as thickener agents to increase the viscosity of the gel. Shin-Etsu HPMC TYLOPUR® DG-4T (Hypromellose 2910) is a suitable thickener for this application due to the stability in and compatibility with organic solvents.

Beside the thickener agent (e.g. HPMC), a humectant (e.g. glycerine, propylene glycol) is needed in the formulation. Additionally, a chelating agent can be used, such as tetra sodium EDTA or sodium citrate. Fragrances and extracts can also be added to the gel. A neutralizing agent, such as sodium hydroxide, can be used to achieve the desired pH.


  • This product meets the requirements of the E 464 (Europe) / INS 464 (USA) specification. Hydroxypropyl Methylcellulose is listed under COSING Ref.No. 34537.
  • CAS No : 9004-65-3
  • INCI Name : Hydroxypropyl Methylcellulose


  • 25 kg card board box

Video – Preparation of Hand Sanitizer Gel using HPMC:

The mentioned Tylopur 60SH-4000 type in the video corresponds to the Tylopur DG-4T.


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BIOGRUND is one of the distributors of Tylopur® DG – 4T.

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