Hypromellose (HPMC) has a good solubility in alcohol. The formulation of hand sanitizer gels use polymers as thickener agents to increase the viscosity of the gel. Shin-Etsu HPMC TYLOPUR® DG-4T (Hypromellose 2910) is a suitable thickener for this application due to the stability in and compatibility with organic solvents.
Beside the thickener agent (e.g. HPMC), a humectant (e.g. glycerine, propylene glycol) is needed in the formulation. Additionally, a chelating agent can be used, such as tetra sodium EDTA or sodium citrate. Fragrances and extracts can also be added to the gel. A neutralizing agent, such as sodium hydroxide, can be used to achieve the desired pH.